Vespolina is an Italian red wine variety. There are plantations mainly in Piedmont, Italy around Gatinaro and Geme. Studies show that the roots of the variety come straight to Piedmont, and according to DNA analyzes, it has a genetic link to the Nebiolo variety. It is mainly used for blending with Croatina and Nebiolo, with which it shares similar spicy characteristics. Despite the similarities between the two varieties, Vespolina has softer tannins that contribute to the production of aromatic wines. The subtle notes are of wild flowers, mushrooms and green tea leaves. In most cases blends of the variety are made, and seldom are entirely varietal wines.

There are many synonyms for Vespolina. Some of the more common are: Balsamina, Canetta, Inzaga, Massana, Nespolina, Vespolino, Vispavola and others.

Vineyards are relatively resistant to disease and infection. They are not susceptible to freezing or powdery mildew. The only disease they get to is powdery mildew.